Botox, Dysport, Xeomin, Jeuveau and Daxxify side by side: what each FDA label says

In short

Five prescription botulinum toxin injections are FDA-approved to improve the look of frown lines between the brows: Botox Cosmetic, Dysport, Xeomin, Jeuveau and Daxxify.¹²³⁴⁵ Their labels differ on which other lines they cover, and Dysport's cosmetic use is limited to adults under 65.

Here is what each label says, what they share, and what that means when you compare brands. This page does not say which is better. The labels aren't head-to-head comparisons.

At a glance

Brands compared

Five

Botox Cosmetic, Dysport, Xeomin, Jeuveau and Daxxify.

Shared use

Frown lines

Glabellar lines, in adults. Dysport: adults under 65.

Shared warning

Boxed warning

Toxin effects can spread beyond the injection site.

Units

Not convertible

Each brand's units are specific to its own product.

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What each label lists

These are the cosmetic uses on each label. Dysport's is for adults under 65. Some of the brands are also approved for medical uses, which we leave out.²³⁵

Cosmetic uses on each FDA label

Brand	Active ingredient	Cosmetic uses on the label
Botox Cosmetic	Active ingredient: onabotulinumtoxinA	Cosmetic uses on the label: Adults: glabellar lines, lateral canthal lines, forehead lines, platysma bands
Dysport	Active ingredient: abobotulinumtoxinA	Cosmetic uses on the label: Glabellar lines, in adults under 65
Xeomin	Active ingredient: incobotulinumtoxinA	Cosmetic uses on the label: Adults: glabellar lines, horizontal forehead lines, lateral canthal lines
Jeuveau	Active ingredient: prabotulinumtoxinA-xvfs	Cosmetic uses on the label: Adults: glabellar lines only
Daxxify	Active ingredient: daxibotulinumtoxinA-lanm	Cosmetic uses on the label: Adults: glabellar lines

Glabellar lines are the frown lines between the eyebrows. Lateral canthal lines are the lines at the outer corners of the eyes, often called crow's feet. Platysma bands are bands in the neck.

Jeuveau's label says it isn't approved for any condition other than glabellar lines.⁴ For any area a label doesn't list, ask what the use is based on.

All five labels carry a boxed warning, the FDA's strongest, about distant spread of toxin effect. The effects of these products may spread from the injection site and cause symptoms of botulinum toxin effects. They have been reported hours to weeks after injection. Swallowing and breathing difficulties can be life threatening, and deaths have been reported.¹²³⁴⁵

All five are prescription drugs. You get them from a licensed provider, and who may inject depends on your state. See our guide to choosing a Botox provider.

Why you can't compare units

The labels agree on this. Each brand's units are specific to its own product and testing method, and can't be compared to or converted into another brand's units.¹²⁴⁵ Xeomin's carton says dosing units of botulinum toxins aren't interchangeable between commercial products.³

So a clinic's price per unit for one brand tells you nothing about another brand's price per unit. Compare the cost of the whole treatment instead. Our Botox cost guide explains how clinics quote.

Myth

A unit of Botox is the same as a unit of Dysport.

Fact

The labels say each brand's units are specific to that product and cannot be compared to or converted into another brand's units.

BOTOX Cosmetic prescribing information, DailyMed, read 29 Oct 2026DYSPORT prescribing information, DailyMed, read 29 Oct 2026

What the labels don't settle

The labels are for each product on its own, and we don't read them as a head-to-head. Whether one suits you better is a question for a provider who knows your face and your history. Our comparison of Botox and Dysport goes into that pair.

At the clinics we list

4,468 of the 7,475 med spas we list offer Botox and 2,199 offer Dysport. The other three brands aren't counted here. Offering a brand doesn't tell you what a clinic stocks, so ask.⁶

60%

of the med spas we list offer Botox; 29% offer Dysport4,468 and 2,199 of 7,475 med spas we list, in 14 states

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Here is what to bring to a consultation.

Questions to bring

The product

Which botulinum toxin will you use, and why that one for me?
Is it approved for the area you plan to treat?
Where do you buy it from?

The price

Is the price per unit, per area or for the whole treatment?
If the brand changes, how does the price change?
What is included, and what is extra?

0 of 6 ticked

Common questions

What is the difference between Botox, Dysport, Xeomin, Jeuveau and Daxxify?

All five are prescription botulinum toxin injections approved for glabellar lines. Botox Cosmetic and Xeomin also list other facial lines, and Dysport is limited to adults under 65. Their active ingredients differ.

Are Botox units the same as Dysport units?

No. Each label says its units are specific to that product and can't be compared to or converted into another brand's units.

Which is best, Botox or the others?

The labels don't rank them and aren't head-to-head comparisons. Ask a provider who knows your history which they would use and why.

Do all botulinum toxins carry the same warning?

Yes. All five labels carry a boxed warning that the toxin's effects can spread beyond the injection site, with swallowing and breathing difficulties that can be life threatening.

Sources (6)

BOTOX Cosmetic prescribing information, DailyMed (set id 485d9b71-6881-42c5-a620-a4360c7192ab) · Allergan Aesthetics, an AbbVie company; FDA-approved labeling (effective 18 Oct 2024 per DailyMed, Medication Guide revised 10/2024). · read 29 Oct 2026
DYSPORT prescribing information, DailyMed (set id 71313a04-1349-4c26-b840-a39e4a3ddaed) · Galderma; FDA-approved labeling (effective 24 Oct 2024 per DailyMed). Covers cosmetic and non-cosmetic uses; this page uses the glabellar line parts. · read 29 Oct 2026
XEOMIN prescribing information, DailyMed (set id ccdc3aae-6e2d-4cd0-a51c-8375bfee9458) · Merz Therapeutics; FDA-approved labeling (effective 10 Jul 2026 per DailyMed). Covers cosmetic and non-cosmetic uses; this page uses the upper facial lines parts. · read 29 Oct 2026
JEUVEAU prescribing information, DailyMed (set id 17a914c1-e54b-4b50-965d-b0fd9111bba4) · Evolus; FDA-approved labeling (effective 28 Apr 2023 per DailyMed). · read 29 Oct 2026
DAXXIFY prescribing information, DailyMed (set id 3aaa6e14-a3f7-4fb2-b9f9-d3a9c3ae1f74) · Revance; FDA-approved labeling (effective 7 Jan 2026 per DailyMed). Covers cosmetic and non-cosmetic uses; this page uses the glabellar line parts. · read 29 Oct 2026
Clinic websites: what they say on their own pages · Our own read of listed clinics' websites in the 14 states we cover, October 2026. A clinic counts once. · read 30 Oct 2026

Where to go next

ComparisonBotox vs Dysport: differences in areas, ages and duration TreatmentBotox: how it works, how long it lasts and the risks TreatmentDysport: cosmetic use, how long it lasts and side effects Cost guideBotox Cost (2026): About $12 a Unit, 2,600+ Clinic Websites GuideHow to choose a Botox provider: what to check and what to ask